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Chronic kidney disease: cardiovascular risk and cardiorenal therapy
Stages CKD by eGFR and albuminuria on the KDIGO heat map and assigns the 2026 ESC CVD–CKD risk category (moderate, high or very high). Recommends a statin-based regimen whatever the LDL-C, with the ESC/EAS LDL-C goals and the dialysis exceptions. Sets out RAS inhibition plus SGLT2 inhibitors, finerenone and semaglutide, and MRA choice in heart failure by LVEF, along with the 120–129 mmHg SBP target and the ESC 2026 advice on ACS, DAPT, DOACs and contrast. Flags the drug-dosing and contrast precautions that matter in cardiology. ESC, ACC/AHA and KDIGO recommendations are shown together.
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Kidney function
Use the eGFR calculator in Basic calculations if needed
Comorbidities and therapy
CKD · KDIGO stage · ESC 2026
Enter the eGFR (and UACR if available).
References
- Damman K, Herrington WG, et al. 2026 ESC Guidelines for the management of cardiovascular disease and chronic kidney disease, in collaboration with the European Renal Association (ERA). Eur Heart J 2026.
- Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int 2024;105(4S):S117-S314.
- Visseren FLJ, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2021;42:3227-3337.
- Marx N, et al. 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes. Eur Heart J 2023;44:4043-4140.
- Mach F, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias. Eur Heart J 2020;41:111-188.
- McEvoy JW, et al. 2024 ESC Guidelines for the management of elevated blood pressure and hypertension. Eur Heart J 2024;45:3912-4018.
- 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the prevention, detection, evaluation and management of high blood pressure in adults. Circulation 2025.
- Grundy SM, et al. 2018 AHA/ACC/multisociety guideline on the management of blood cholesterol. Circulation 2019;139:e1082-e1143.
- KDIGO 2021 clinical practice guideline for the management of blood pressure in chronic kidney disease. Kidney Int 2021;99(3S):S1-S87.
- KDIGO 2022 clinical practice guideline for diabetes management in chronic kidney disease. Kidney Int 2022;102(5S):S1-S127.
- Perkovic V, et al. Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes (FLOW). N Engl J Med 2024;391:109-121.
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