Heart failure
ICD / CRT-D indications
Combines secondary- and primary-prevention ICD criteria with CRT indications to suggest the appropriate device.
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Secondary prevention
Cardiomyopathy
Cardiomyopathy (must be entered)
NYHA class (must be entered)
Conditions
Tap all that apply
Device recommendation
Enter the cardiomyopathy, NYHA class, LVEF and QRS.
- ⚠ Cardiomyopathy type and NYHA class must be entered for a primary-prevention ICD or CRT decision.
Notes: ICD indications
ESC vs ACC/AHA
ESC
- Secondary preventionIESC 2022Survived VF or haemodynamically unstable VT without a reversible cause, expected survival > 1 year.
- Ischaemic cardiomyopathyIESC 2022LVEF ≤ 35%, NYHA II–III after ≥ 3 months OMT, ≥ 6 weeks post-MI.
- Ischaemic, NYHA IIIaESC 2022LVEF ≤ 30% despite ≥ 3 months OMT.
- Non-ischaemic cardiomyopathyIIaESC 2021/2022LVEF ≤ 35%, NYHA II–III after ≥ 3 months OMT (DANISH). Favoured by LGE on CMR, high-risk genes (LMNA, FLNC, PLN, RBM20) and age < 70.
- Not recommendedIIIESC 2022NYHA IV refractory to drugs unless a candidate for CRT, LVAD or transplant; within 40 days of MI for primary prevention.
ACC/AHA
- Secondary prevention1ACC/AHA 2017Cardiac arrest from VF or haemodynamically unstable VT, or stable sustained VT, without a reversible cause, survival > 1 year.
- Ischaemic cardiomyopathy1ACC/AHA 2022LVEF ≤ 35%, NYHA II–III on GDMT, ≥ 40 days post-MI and ≥ 90 days post-revascularisation.
- Ischaemic, NYHA I1ACC/AHA 2022LVEF ≤ 30%, ≥ 40 days post-MI on GDMT (MADIT-II).
- Non-ischaemic cardiomyopathy1ACC/AHA 2022LVEF ≤ 35%, NYHA II–III on ≥ 3 months GDMT.
- Not recommended3ACC/AHA 2017NYHA IV on drugs who are not candidates for CRT, LVAD or transplant; survival < 1 year.
Note: CRT-D
- CRT-D when both indications are metIESC 2022 · ACC/AHA 2022CRT indication (LVEF ≤ 35%, QRS ≥ 130 ms, NYHA II–IV ambulatory) plus an ICD indication → CRT-D rather than ICD alone.
- Ischaemic cardiomyopathy favours CRT-DESC 2021Sudden-death risk stays high after CRT; prefer CRT-D when survival > 1 year.
- Consider CRT-P insteadESC 2021Non-ischaemic cardiomyopathy, age > 70–75, NYHA IV, frailty or major comorbidity, survival < 1 year or the patient’s choice (DANISH: no mortality benefit of ICD on top of CRT in non-ischaemic disease).
References
- Zeppenfeld K, et al. 2022 ESC Guidelines for ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J 2022;43:3997-4126.
- Glikson M, et al. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J 2021;42:3427-3520.
- McDonagh TA, et al. 2021 ESC Guidelines for heart failure (and 2023 focused update). Eur Heart J 2021;42:3599-3726.
- Al-Khatib SM, et al. 2017 AHA/ACC/HRS Guideline for ventricular arrhythmias and prevention of SCD. Circulation 2018;138:e272-e391.
- Heidenreich PA, et al. 2022 AHA/ACC/HFSA Guideline for the management of heart failure. Circulation 2022;145:e895-e1032.