Launched on 6th of October 2026

Cardio.toolsby Mohamed Ghazy, MD CardiologyAin Shams University, Egypt · Cardiology Consultant, Saudi ArabiaScopus ID: 55257919100
Cardiovascular disease in pregnancy

CARPREG II

Ten predictors (general, lesion-specific and delivery-of-care) estimate the risk of a primary maternal cardiac event in pregnancy: cardiac death, arrest, arrhythmia needing treatment, heart failure, stroke, MI or vascular dissection. Use it with the mWHO 2.0 class.

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Criteria
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  • Derived and validated in 1938 pregnancies (Toronto). Combine with the lesion-based mWHO 2.0 class.
Total score
0
Low risk
Maternal cardiac event ≈ 5%
Decision guide
Care in a local hospital with cardiology review; follow-up per mWHO class.
Ranges: 0–1 Low risk2 Intermediate risk3 Intermediate–high risk4 High risk5–21 Very high risk
References
  1. Silversides CK, et al. Pregnancy outcomes in women with heart disease: the CARPREG II study. J Am Coll Cardiol 2018;71:2419-2430.
  2. De Backer J, Haugaa KH, et al. 2025 ESC Guidelines for the management of cardiovascular disease and pregnancy. Eur Heart J 2025.
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