PE diagnostic & treatment pathway

Step-by-step ESC 2019 algorithm (haemodynamic status, clinical probability, D-dimer, CTPA and risk class: high, intermediate-high, intermediate-low, low) beside the ACC/AHA 2026 clinical categories A–E with management from both guidelines side by side.

Upload a report, lab sheet or echo picture to fill this calculator automatically.

ESC 2019 and ACC/AHA 2026 pathway

Answer each step — the next one unlocks

Haemodynamic instability?

Cardiac arrest, obstructive shock (SBP < 90 or vasopressors + end-organ hypoperfusion), or persistent hypotension (SBP < 90 or drop ≥ 40 mmHg for > 15 min).

Pathway outcome

Work through the steps on the left.

References

Konstantinides SV, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J 2020;41:543-603.
Creager MA, et al. 2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the evaluation and management of acute pulmonary embolism in adults. Circulation 2026;153:e977-e1051.
Righini M, et al. Age-adjusted D-dimer cutoff levels to rule out PE (ADJUST-PE). JAMA 2014;311:1117-1124.