Pulmonary embolism
VTE-BLEED
Six-item score (Klok 2016) derived in RE-COVER and validated in Hokusai-VTE and real-world cohorts. A score ≥ 2 marks high bleeding risk during anticoagulation after the first month, helping decide on extended treatment and dose.
Upload a report, lab sheet or echo picture to fill this calculator automatically.
Criteria
Tap every item that applies
Total score
0
Low bleeding risk
Bleeding ≈ 2.8% over the RE-COVER follow-up (74% of patients)
Decision guide
Bleeding risk does not argue against extended anticoagulation when the recurrence risk warrants it. Reassess yearly.
Ranges: 0–1.5 Low bleeding risk2–9 High bleeding risk
References
- Klok FA, et al. Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. Eur Respir J 2016;48:1369-1376.
- Klok FA, et al. External validation of the VTE-BLEED score for predicting major bleeding in patients with venous thromboembolism. Thromb Haemost 2017;117:1164-1170.
- Konstantinides SV, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J 2020;41:543-603.
More in Pulmonary embolism
PE diagnosis
PE prognosis & management
Bleeding risk on anticoagulation
Anticoagulation duration & recurrence
Cancer-associated VTE